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Besides that, A-T is a rare disease (OMIM 208,900) in which incidence ranges from 1: 40,000 to 1: 100,000, and it is caused by a mutation in the ATM gene (ataxia-telangiectasia mutated)

We also provided a novel perspective on characterizing the fluctuation in repeated measurements of multiple environmental chemicals and identifying the potential critical windows

Conversely, cartilage-specific overexpression of GPX4 via transgenic technology, or restoration of its activity using small molecule drugs such as certain natural compounds or ferroptosis inhibitors, can significantly delay cartilage degeneration, improve subchondral bone sclerosis and osteophyte formation, and alleviate synovitis in model animals (Xiao et al., 2024), which directly confirms the protective role of GPX4 in OA progression from a gain-of-function perspective

doi: 10.1073/pnas.71.9.3329

These effects may be related to autoimmunity of alopecia areata

Upon reaching the tumor site, stealth liposomes primarily remain within the extracellular matrix rather than entering tumor cells directly