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HDL-induced NO underlies many of HDLs beneficial properties to endothelial cells, including HDL-induced vasodilation, tightening of cell-to-cell junctions and increased barrier function, differentiation of endothelial progenitor cells, cell survival and proliferation, cell migration, inhibition of apoptosis, and suppression of adhesion molecule expression
doi: 10.1038/s41598-022-05197-9
W., da Silva, L., Maciel, G., Huguenin, A
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When bacteria or related metabolites enter the bloodstream, they can activate TLRs and NLRs receptors on platelets, thereby promoting the release of inflammatory factors
