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That efficiency is its core advantage and exactly why the question of frequency deserves more than a general recommendation

Inhibitory synapses are repeatedly assembled and removed at persistent sites in vivo

[DOI] [PMC free article] [PubMed] [Google Scholar] Hu LT, Eskildsen MA, Masgala C, Steere AC, Arner EC, Pratta MA, Grodzinsky AJ, Loening A, and Perides G (2001)

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It acts as a powerful shield against harmful toxins and free radicals that can accumulate within various organs, including the liver, lungs, intestines, and kidneys

Blood 78(Suppl 1):295a, 1991