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An early analysis of the results of 12 randomized controlled trials showed that folic acid supplementation (0.5-5 mg/day) had the greatest lowering effect on blood homocysteine concentrations (25% decrease)

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(4) In the clinical evidence-based analysis, 3 randomized controlled studies reported that oral vitamin B12 supplementation was as effective as vitamin B12 intramuscular injections in treating patients with vitamin B12 deficiency

found only in foods of animal origin Foods that are high in vitamin B 12 (g/100g) include: Liver (2658) Beef and lamb (13 Chicken (trace) Eggs (12.5) Dairy foods (0.32.4) In normal humans the absorption of vitamin B 12 from foods has been shown to vary depending on the quantity and type of protein consumed

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Dosing tiers: Splitting the dose into two administrations (AM and PM) maintains more consistent lipolytic signaling across a 24-hour period