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doi:10.1016/j.ijwd.2019.10.007 Karadag AS, Ertugrul DT, Tutal E, Akin KO
Benchmarking and Preclinical Evaluation of Drug Candidates Preclinical drug and target discovery for obesity is a highly competitive area
Triple agonists [12] such as GLP-1RA, GIP-RA plus glucagon-RA are in development and may show comparable efficacy in weight loss to tirzepatide by targeting multiple pathways involved in energy regulation [13]
As endothelial cells die, the blood vessels feeding the fat tissue shrink and collapse
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