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CL values ranged from 1.76 to 3.15 mL/h/kg in rats and 0.99 to 2.63 mL/h/kg in monkeys (Table 2)

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As shown in Figure 8, all of these compounds were associated with multiple targets, and 1,086 component-target associations existed between the 12 compounds and 235 targets

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It has also been shown that impaired baroreceptor reflexes are caused by reduced inhibition of the vagus and parasympathetic nerves (123)