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In cells, lipoic acid is swiftly reduced to dihydrolipoic acid, and in vitro studies indicate that dihydrolipoic acid is then rapidly exported from cells (3)

doi: 10.3389/fncel.2020.00163, 76 KhlerS.SchmidtH.FlleP.HirrlingerJ.WinklerU

10.1016/j.freeradbiomed.2012.02.043 65

doi: 10.1111/j.1471-4159.2009.06542.x

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Animals were sacrificed at 0.5, 1, 4, 24 hours and 1, 2, and 3 weeks after TNBS+ethanol administration and colonic mucosa was obtained for evaluation of damage, GSH content, total RNA isolation and protein content