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Up to now, in addition to mitochondrial oxidative stress, many other cellular processes, including phase I/phase II metabolism, endoplasmic reticulum stress, autophagy, sterile inflammation, microcirculatory dysfunction, and liver regeneration, have been identified to be involved in the pathogenesis of AILI, providing new targets for developing more effective therapeutic interventions against APAP-induced liver injury

Torres, MD, DPDS Dermatology Makati Medical Center

Design, physicochemical characterization, and in vitro permeation of innovative resatorvid topical formulations for targeted skin drug delivery

While this outcome underscores the critical involvement of mitochondria in ferroptosis, the precise nature of their role remains unclear and warrants further investigation [51]

Control of cell death in health and disease

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