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This action on the P450 protein levels and activity is mediated by the hypothalamic-pituitary axis, which can stimulate or suppress hormone release, including growth hormone, corticosterone, and thyroid hormones

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These growth factors stimulate collagen formation, new blood vessel growth, and improved tissue elasticity for natural, lasting enhancement not just temporary swelling

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E.Koitka-WeberA.MattheusM.von EynattenM.et al (2017)