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The median CA 19-9 level, a prognostic marker commonly used to reflect disease burden and PDAC aggressiveness, was similar between groups at diagnosis, although it trended towards a higher value in the high glucose group (2439.5 U/mL high glucose vs 1294.5 U/mL normal glucose, P =0.224)

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The GRADE assessment showed moderate certainty of evidence for the increase in serum vitamin B12 levels and low certainty of evidence for homocysteine reduction, both across all studies and within RCT-only and observational-only subgroups

P., Andrade, C

A mortality rate of 118% has been reported in such patients [14, 15]

Severe COVID-19 pneumonia: pathogenesis and clinical management