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This underdiagnosis can lead, besides death in 20% when it is not appropriately treated, to Korsakoffs syndrome, a severe dysfunction often following untreated Wernickes encephalopathy, that does not remit even with thiamine treatment and is associated with chronic alcohol abuse and chronic thiamine deficiency (, , , )

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Inject the medication slowly and steadily

For microdosing protocols below 2mg, 5mg/mL provides better syringe measurement accuracy

Chronic inflammation, which leads to pain and disability, is thought to be a dysregulation of an appropriate inflammatory process

Some people who do not get enough B12 naturally in their diet
