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Current work is dissecting the upstream activators and downstream effectors of Rho GTPase in hematopoietic stem cells

It has been demonstrated that obesity-associated induction of MT expression in adipose tissue is a protective response, being at least partially mediated through modulation of oxidative and endoplasmic reticulum stress [62]

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Previous reports from our laboratory showed that 15LO1 also contributes to downstream T2 immunoinflammatory responses (6, 10, 14, 28)