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Pharmacological stimulation of brain carnitine palmitoyl-transferase-1 decreases food intake and body weight

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Nicotinamide adenine dinucleotide (NADH) and acetyl-CoA, two metabolic intermediates produced in the course of FAO, induce activation of PDK, which in turn phospho-inactivates the E1 subunit of the PDH complex, leading to lower rates of glucose oxidation and higher rates of lactate release 70

Dizziness or fainting is caused by hypotension, especially orthostatic hypotension when one stands up
