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The effector CD38 low/- NK cells show a high proliferative potential and functional activity in the presence of CD38 mAb by inducing ADCC in the stressed tumor microenvironmental condition

It has been identified that the length, start-site consensus sequence, secondary structures, upstream open reading frame, upstream the canonical AUG, internal ribosome entry site (IRES) and sequences that bind regulatory proteins present in 5UTR are responsible for the regulation of mRNA translation rate [ It is known that some UTRs present in human genome promote higher translation rates than other UTRs