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The permeability transition pore complex: another view
Biochem Biophys Res Commun 324 : 231235 Wong A, Yang J, Cavadini P, Gellera C, Lonnerdal B, Taroni F, Cortopassi G 1999 The Friedreich's ataxia mutation confers cellular sensitivity to oxidant stress which is rescued by chelators of iron and calcium and inhibitors of apoptosis
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Its advantageous effects in managing these conditions stem from its potent antioxidant and anti-inflammatory properties, its capacity to counteract abnormal lipid levels, and its essential role in maintaining mitochondrial function [29]