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The significant cardio-renal benefits of metformin and SGLT-2i beyond glycemic control have led to the emergence of an integrated treatment model that can be applied to manage DPD

GST-fusion proteins were purified on glutathione agarose 4B beads (Thermo Fisher Sci)

Each cuvette contained 50 mM Tris-HCl (pH 7.4) buffer, 75 mM sodium chloride, 0.01 M sodium cyanide, 0.5 mM MTT, 0.2 mM PMS, and 0.2 ml of cell extract

Simon DK, Wu C, Tilley BC, Lohmann K, Klein C, Payami H, Wills AM, Aminoff MJ, Bainbridge J, Dewey R, Hauser RA, Schaake S, Schneider JS, Sharma S, Singer C, Tanner CM, Truong D, Wei P, Wong PS, Yang T

B., Soberanes, S., Sullivan, L