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Proceedings of the National Academy of Sciences of the United States of America, 67, 12481255

A.Raja SinghP.MukherjeeS.ElumalaiP.DasS.et al (2016)

CMAJ 185(9):E363E364

Enhanced doxorubicin delivery to the brain administered through glutathione PEGylated liposomal doxorubicin (2B3-101) as compared with generic Caelyx,((R))/Doxil((R))a cerebral open flow microperfusion pilot study

This enzyme hydrolyzes GSH to its amino acid components, among which cysteine is used for the intracellular GSH resynthesis [16]

Decreased scavenge and increased formation of cytokines activates naive neutrophils, causing a feed-forward loop of excessive inflammation in diabetes [17, 18]