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The potential mechanisms involve the suppression of melatonin secretion via the ipRGCs-SCN pathway, leading to dysregulation of HPO axis function and disruption of circadian clock gene expression in the ovaries and uterus

Dose optimization of topical tranexamic acid for primary total hip arthroplasty: a prospective cohort study

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Available at: (Accessed 20/02/2022)

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This restoration of metabolic cofactor availability enables enhanced function of NAD+-dependent enzymes including sirtuins, poly(ADP-ribose) polymerases, and various deacetylases that regulate cellular metabolism, stress responses, and aging processes