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The Effects of Insulin-Like Growth Factor 1 on Mitophagy Up to now, numerous studies have reported the relationship between IGF1 and autophagy
Kachhawa D, Vats G, Sonare D, et al
Hepatology 54 , 252261 (2011)
Oncogene 34 , 51285140 (2015)
On the other hand, inhibition of GSH synthesis with BSO, independently of the cysteine pool, has been repeatedly described to induce ferroptosis ( via depletion of mitochondrial GSH pool leading to the release of cytochrome c, when combined with chemotherapy in breast cancer and leukemia, respectively (71, 72)
The exercise connection One of the most intriguing aspects of MOTS-c research is its connection to exercise
