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AOD9604 is bioavailable orally, with MS peptide analysis confirming appearance in pig plasma following oral dosing, and degradation occurring primarily via sequential N-terminal amino acid removal in a cascade fashion

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v/v) heat-inactivated FBS (GE HyClone) and 1% (v/v) penicillin/streptomycin (Gibco) at 37 C and 5% CO 2

We used a slice thickness of 0.5 mm and 29 slices with a scan time of 15 min to image the whole brain

Curcumin's ability to penetrate mitochondria safeguards against oxidative damage and prevents mitochondrial dysfunction [148]

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