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Neurodegenerative disease Neurodegeneration is an age-related pathological condition that results in the loss of neural structure and function, often accompanied by abnormal cell death, including apoptosis, necrosis, necroptosis, oxytosis, and ferroptosis

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37 Low NAD+ has also been found to promote senescence by reducing SIRT1 activity, which in turn reduces p63 expression, leading to a reduction in cell proliferation

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Identification and clonal characterisation of a progenitor cell sub-population in normal human articular cartilage