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As both these approaches targeted the active site, we shifted to developing two high-throughput, robust, yeast-based assays that were active site independent

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Biochemical and Biophysical Research Communications, 430(2), 614619

However, forced telomerase expression in cells and mice with normal-length telomeres has shown that telomerase promotes growth and survival in a manner that is uncoupled from net telomere lengthening
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