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In 2019, Professor Zhao Yingmings team made a groundbreaking discovery, identifying lactyl-CoA-mediated histone L-lysine lactylation (Kla) in human breast cancer MCF-7 cells and its involvement in gene expression regulation

Science 316 , 11601166 (2007)

Therefore, the antioxidant defence systems play a vital role in maintaining an optimal redox balance in melanocytes by quenching ROS and protecting against oxidative stress, excessive melanogenesis and photo-damaged skin

Brain 141:19001916

So, it's important for these patients to consult their physician quickly and for the physician to fit them into their clinic, because they can get quite unwell quite quickly

Branchedchain amino acid metabolism: Pathophysiological mechanism and therapeutic intervention in metabolic diseases