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Ethical approvals for the use of human material All uses of human material have been approved for this study

Differentially expressed between tissues, SLC22A4 is notably highly expressed both on the apical membrane of the small intestine where it functions in a pH-dependent fashion to take ergothioneine up from the diet (29) and on the apical membrane of proximal tubular cells in the kidney where it functions in renal reabsorption (30)

10.1016/j.fitote.2005.03.015 130 PieroniA.HovsepyanR.ManduzaiA

Antioxidants 8(5):126

Neagoe I, Liu C, Stumpf A, Lu Y, He D, Francis R, et al

And those randomized to even just a half cup of kales worth of the cruciferous compound sulforaphane got significant improvements in processing speed and working memory