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Elevated levels of 4-HNE covalently modify scaffold proteins such as GM130 and GRASP65, resulting in Golgi stack disassembly and fragmentation
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elegans , suggesting that these pathways may be linked and that environmental contributors to neurodegenerative disease may proceed through pathways implicated in familial forms
Systemic delivery of scAAV9 expressing SMN prolongs survival in a model of spinal muscular atrophy
Mitochondria and microbiota dysfunction in COVID-19 pathogenesis
