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Specifically, MYC upregulates the glutamine transporter and induces the expression of GLS at both mRNA and protein levels [84, 85]

Secondly, accurately detecting nROS currently poses significant challenges owing to the difficulties associated with fluorescent probes crossing the nuclear membrane and avoiding DNA damage response (DDR) pathways

Altogether, redox-sensitive epigenetic changes compromise both transcriptional regulation and metabolic competence in aging oocytes

These oocytes were maintained in M2 medium under liquid paraffin oil at 37C with 5% CO [2]

The patients on long-term humidification therapy showed significantly fewer exacerbation days, increased time to first exacerbation, improvement in quality of life and lung function

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