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To view a copy of this licence, visit About this article Cite this article Fang, YQ., Ding, H., Li, T

Additionally, vitamin B12 deficiency can cause neurocognitive manifestations including depression, episodes of psychosis, delirium, dementia, poor memory performance, and cognitive impairment ( In 1978, Carney and Sheffield found that 31% of patients suffering from depression had low serum vitamin B12 levels (65)

2 Pathogenesis of Fibromyalgia The fact that pain is the hallmark of fibromyalgia has caused experts to believe that the disorder is neurogenic in origin, as it is associated with a central amplification of pain perception characterized most prominently by hyperalgesia (increased response to painful stimuli) and allodynia (pain from stimuli not normally painful)