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Purification and properties of S-formylglutathione hydrolase from human liver

Gallelli JF

When the liver is functioning optimally, it can spare more glutathione for the rest of the body, including the joints

Briefly, the detergent, DTT and other low-molecular-weight components were removed using 200 l UA buffer by repeated ultrafiltration facilitated by centrifugation

[DOI] [PubMed] [Google Scholar] Hughes KC, Gao X, Kim IY, Rimm EB, Wang M, Weisskopf MG, Schwarzschild MA, Ascherio A

In the future, the integration of metabolomic readouts, single-cell and spatial transcriptomic localization, and metabolic modeling analysis is expected to establish a research framework of metabolic stratification-target selection-efficacy prediction, thereby reducing the risk of failed extrapolation across different diseases or populations (138)