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According to a 2017 systematic review in the Journal of Clinical Nursing confirming that aspiration before subcutaneous injection does not reduce adverse events, subcutaneous injections carry a distinct pharmacokinetic profile that intramuscular delivery disrupts, which is why correct angle and depth matter for predictable results

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2.5 Characterization of surface morphology The surface morphology of the PLGA/CNT-lam scaffolds, PCL conduits, and the whole structure of conduits were analyzed by scanning electron microscopy (SEM, XL 30, Philips, USA)

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