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Ethics declarations Ethics approval and consent to participate All procedures performed in studies involving human participants were in accordance with the ethical standards of Royan Institute and the 1964 Helsinki declaration and its later amendments or comparable ethical standards (Ethics approval number: IR.ACECR.ROYAN.REC.1397.156)

Data processing: All data were acquired and processed using SCIEX OS software 2.1.0

doi: 10.1126/science.1224631 89

Understanding how your heart responds to physical activity is crucial when trying to pinpoint what causes heart palpitations

For instance, it promotes macrophage polarization (87), resulting in a 50% increase in M2-type macrophages and a 50% decrease in M1-type macrophages (88)