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Hong S, Moreno-Navarrete JM, Wei X, Kikukawa Y, Tzameli I, Prasad D, Lee Y, Asara JM, Fernandez-Real JM, Maratos-Flier E, Pissios P. Nicotinamide N-methyltransferase regulates hepatic nutrient metabolism through Sirt1 protein stabilization. Nat Med. 2015 Aug;21(8):887-94. doi: 10.1038/nm.3882. Epub 2015 Jul 13. PMID: 26168293; PMCID: PMC4529375
Enhanced Immune Function: Vitamin B12 is vital for a robust immune system
It's attracted growing interest in research circles because of how directly it targets a specific enzymatic pathway - which makes it a useful tool for studying how NNMT activity influences downstream metabolic signalling at the cellular level
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