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During this process, the release of DAMPs and cytokines prompts the maturation of dendritic cells and the activation of tumor-specific T cells, thereby facilitating the infiltration of cytotoxic T lymphocytes (CTLs) into the TME (Wang et al., 2023)

The resulting puromycin-resistant cells were used as a pooled population without single-cell cloning, and thus likely contained a small fraction of FBXL5-intact cells

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Additionally, T4s immunomodulatory properties have been emphasised in studies demonstrating its capacity to enhance survival rates in viral infections by balancing the host immune response [90]

Such a decay rate arises from a first-order reaction where the rate of elimination is proportional to the amount of the substance: [41] The half-life for this process is [41] Alternatively, half-life is given by where z is the slope of the terminal phase of the timeconcentration curve for the substance on a semilogarithmic scale