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Economies of scale may be limited for peptide drugs treating rare conditions, where small patient populations cannot support large-scale manufacturing investments

Vasopressin, for instance, is an anti-diuretic peptide

Total RNA was extracted from the cell lysates using an EZ1 RNA Cell Mini Kit (Qiagen GmbH) on EZ1 Advanced XL automated RNA purification instrument (Qiagen GmbH) following the manufacturer's instruction

Therefore, the data were pooled for a given treatment (SL, PO) to analyze the results ( n =20 for each treatment)

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These studies are incredibly promising but are not a substitute for human trials