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Pemov A, Hansen NF, Sindiri S, Patidar R, Higham CS, Dombi E, et al

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Apos, as communicators of lipoproteins, are also involve in lipids metabolism through modulating enzymes activity and binding to cellular receptors

Flexibility in charge is essential during LNP preparation, maintaining a neutral surface charge at physiological pH to prevent immune responses while becoming positively charged in endosomal environments for membrane fusion and effective cytoplasmic release [40]

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pmid:22094400