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Ligands are immobilized to the solid support material by one of two ways: Formation of covalent bonds between particular functional groups (e.g., primary amines, aldehydes, carboxylic acids, sulfhydryls) and the reactive groups Indirect coupling methods

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ROS Scavenging and Gene Regulation: Oxidative stress upregulates the Microphthalmia-associated Transcription Factor (MITF), which acts as the primary on-switch for melanin production [5]

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As for the costs, they can vary depending on several factors, such as the location of the clinic, the expertise of the healthcare providers, and the specific needs