glutathione metabolism and its role in hepatotoxicity Frontiers Dysregulation of glutathione synthesis in
Description
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The noncanonical NF-B pathway
Krppel-like transcription factors have three conserved C2H2-type zinc fingers at the C-terminus that are involved in DNA binding and directly interact with GATA1 (54)
[DOI] [PubMed] [Google Scholar] Gardner R
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Glutathione is synthesized in the cytosol of each cell by the action of two enzymes in an elegantly regulated system that allows it to be maintained at different homeostatic levels in different tissue types, with the liver, given its detoxification role, having the highest amounts
