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People (particularly those with light skin) who spend a lot of time in the sun are more likely to develop liver spots over time, as their bodies start to produce melanin in higher concentrations, or it clumps together

Among the biomarkers implicated in cell cycle, DNA damage/repair, apoptosis, senescence and oxidative stress, only ATM was consistently expressed in hair follicle melanocytes in situ and correlated to the pigmentary status of the hair bulb

It inhibits the pigment responsible for dark spots and uneven skin tone, leading to a more even complexion and reduced hyperpigmentation

This activation is crucial for its anti-fibrotic effects
