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Topical capsaicin treatment alleviates itching symptoms in patients with PN, normalizes TRPV1 expression in skin lesions, and reduces SP and CGRP levels (127)

It is released by various cell types, including platelets

This is a theoretical concern from epidemiological data, not a demonstrated side effect of CJC-1295, but it warrants monitoring (Renehan et al., Lancet 2004)

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