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It holds the promise to treat difficult and poor prognostic diseases such as cancers, complex infections, autoimmune diseases, and other clinical problems (Shen et al., 2018

Wong CH, Bozinovski S, Hertzog PJ, Hickey MJ, Crack PJ

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Thyroid function tests typically revealed suppressed TSH levels with elevated free T4 and/or free T3, and over 90% of patients tested positive for TRAb, confirming the autoimmune nature of the condition

One of the key aspects of diagnosing this disorder, aside from having a clinical suspicion in the setting of anion gap metabolic acidosis without another explanation, is the detection of 5-oxoproline in the urine

Immunopathogenesis of Rheumatoid Arthritis