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You can, but results are much better when paired with exercise and a healthy diet
According to Kaplan et al., intra-VTA A 1 R agonism suppresses morphines effects on motor activity and VTA projections neural activation, including Fos immunoreactivity in the nucleus accumbens [80]
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Homge M, Pinkel D, van Dekken H, Brochstein J, Kernan NA, O'Reilly RI, Segraves R, Gray J, Andreeff M
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