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These complexes can deposit on hepatocyte membranes or LSECs, activating the complement system and triggering local inflammatory responses, leading to hepatocyte damage [89]

KD inhibit the activation of synthesize 3-hydroxy-3-methylglutaryl-CoA (HMG CoA) while activating HMG-CoA lyase (HMGCL), thereby promoting the production of ketone bodies and concurrently reducing the synthesis of endogenous total cholesterol (TC) [88, 89]

Austin Diabetes Res

(2022) 9(8):ofac397
