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By blocking NNMT, it may support cellular NAD+ levels and metabolic function

[DOI] [PMC free article] [PubMed] [Google Scholar] 18.Philippou A., Armakolas A., Panteleakou Z., Pissimissis N., Nezos A., Theos A., Kaparelou M., Armakolas N., Pneumaticos S.G., Koutsilieris M

Older adults may experience age-related changes in their digestive system that reduce B12 uptake

So meanwhile

Those who received only Alimta and cisplatin had a median survival of 16.1 months
With B12 injections, all the dose is delivered into the bloodstream, so you get the maximum benefit
