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While native MGF is rapidly degraded within minutes, PEGylation significantly prolongs its half-life, making it more practical for research into muscle repair, recovery, and tissue regeneration

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GPX4 uses reduced GSH to reduce toxic lipid peroxides (such as phosphatidylethanolamine hydroperoxide, PE-OOH) to non-toxic lipid alcohols through the selenocysteine residue in its active center, thereby maintaining cell membrane stability and blocking the ferroptosis process ( There is significant heterogeneity in the effects of ferroptosis on T cell subsets: CD8+ T cells are highly sensitive to GPX4 inhibitors (such as RSL3), and low doses of the drug can induce ferroptosis

Histology The right Achilles tendon together with a part of the calf muscle was harvested, incubated in sucrose solution (15% followed by 30%) and then optimal cutting temperature compound (OCT

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To learn more about the specific biological roles of GSH-Px in L