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To test the hypothesis that a disorder of ROS homeostasis is induced by OsG-produced oxidative stress, an antioxidant, GSH (50 mg/kg/ 6 h), was subcutaneously injected into animals with LOsG challenge as described above, defined as the LOsG.TdGSH group ( n = 10)

Intracranial hypertension (papilledema) Intracranial hypertension occurred in 3 of the 71 Increlex subjects

Jan 2015;11(1):362-366

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Then the amino group of glycine participates in a nucleophilic attack, displacing the phosphate group and forming GSH