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Table of Contents Toggle The Unique Toxicology Challenge of an Orphan Peptide The absence of an identified receptor for BPC-157 an unusual characteristic for a peptide with such extensively documented biological effects means that the standard pharmacological approach to toxicology assessment cannot be applied with the same confidence used for receptor-defined peptide agents

This dual-response characteristic can effectively distinguish the enzyme activity differences between tumors and normal tissues (such as CES1 in liver and CES2 in tumors)

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[Google Scholar] 215.Haylor J

Therefore, the GPx-like catalytic activity of compounds was studied using glutathione (GSH) as thiol cofactor and hydrogen peroxide (H 2 O 2 ) as substrate [57, 58]

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