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These reversible modifications are playing essential roles in gene regulation, X-inactivation, imprinting, and silencing of parasitic DNA elements ( PATHOLOGICAL ALTERATIONS OF GSTP1 METHYLATION PATTERNS DNA methylation, the addition of a methyl-group to cytosines is the most common epigenetic modification, inducing the reorganization of the gene locus and thus regulating gene expression (Smith and Meissner, 2013)

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Taurine protected motor neuron loss in amyotrophic lateral sclerosis transgenic mice, in which heat shock factor 1 - mediated TauT expression partly defends motor neurons by preventing oxidative stress [97]