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AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function

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Maintenance of these structures are crucial, because the dysregulation of tight junction proteins during injurious events, such as in celiac disease or intestinal ischemia, and the inability to repair tight junction structures after injury can result in intestinal inflammation, sepsis, and multiple organ dysfunction in clinical patients (16, 17)

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Iwakura et al., 2008

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