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The cGAS-STING pathway can also be activated by tumor-derived dsDNA to induce IFN-I, which can promote the maturation/activation of tumor-infiltrating dendritic cell (DCs) or macrophages and enhance the presentation of tumor-specific antigens to activate CD8+T cells and NK cells for tumor immune responses (41, 42)

Interleukin-10 mitigates doxorubicin-induced endoplasmic reticulum stress as well as cardiomyopathy

Since NFIA transcriptionally upregulates IGFBP2 , miR-302b suppression enhances IGFBP-2-dependent oncogenesis both directly, and indirectly through NFIA [44]

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In contrast, the knockdown of GPX2 did not affect the expression of chemoresistance proteins but slightly increased the expression of ABCC1 (Supplementary Fig