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The risk differences (drug versus placebo), however, were relatively stable within age strata and across indications

In the blood, once secreted from the pineal gland, melatonin is usually bound to albumin, metabolized to 6-hydroxymelatonin by cytochrome P-450 isoforms and conjugated, in the liver, to produce the principal urinary metabolite, 6-sulfatoxy-melatonin, which is finally eliminated through the kidney 14

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Manufactured in ISO-certified facilities and validated by rigorous HPLC and endotoxin testing, every vial ensures reproducible, high-quality results