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In the present study, we investigated the expression of SA markers and their regulatory proteins in keloids

All protocol-level guidance is based on published data and preclinical evidence cited inline

Regarding MAPK1 and MAPK3, studies have reported that they are involved in BRCA through several approaches, including the activation of cell cycle-related proteins and inhibition of antiapoptotic proteins by MAPK1/MAPK3 phosphorylation, and regulation of cytoskeletal proteins to promote migration 36

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A third interaction region involves a set of inter- and intra-molecular, antiparallel -bridges formed between hTrxR1 residues 495 hTrxR1 to 499 hTrxR1 and hTrx1 residues 72 hTrx1 to 75 hTrx1 (Fig